Blood Cancer

Blood cancers affect the production and function of your blood cells. Most of these cancers start in your bone marrow where blood is produced. Stem cells in your bone marrow mature and develop into three types of blood cells: red blood cells, white blood cells, or platelets. In most blood cancers, the normal blood cell development process is interrupted by uncontrolled growth of an abnormal type of blood cell. These abnormal blood cells, or cancerous cells, prevent your blood from performing many of its functions, like fighting off infections or preventing serious bleeding.
There are three main types of blood cancers:

Leukemia, a type of cancer found in your blood and bone marrow, is caused by the rapid production of abnormal white blood cells. The high number of abnormal white blood cells are not able to fight infection, and they impair the ability of the bone marrow to produce red blood cells and platelets.

Lymphoma is a type of blood cancer that affects the lymphatic system, which removes excess fluids from your body and produces immune cells. Lymphocytes are a type of white blood cell that fight infection. Abnormal lymphocytes become lymphoma cells, which multiply and collect in your lymph nodes and other tissues. Over time, these cancerous cells impair your immune system.

Myeloma is a cancer of the plasma cells. Plasma cells are white blood cells that produce disease- and infection-fighting antibodies in your body. Myeloma cells prevent the normal production of antibodies, leaving your body's immune system weakened and susceptible to infection.
Non-Hodgkin lymphoma is the sixth most common cancer in the UK
Leukaemia is the eleventh most common cancer in the UK
Other types of blood cancer – such as myeloma – are less common.
Myelodysplastic syndromes (MDS)
The myelodysplastic syndromes (MDS) are a group of blood disorders where a person’s bone marrow is not producing the correct amount and quality of blood cells. Red, white and platelet cells can be affected.
These problems lead to people with MDS feeling very tired, weak and bleeding or bruising more easily.  There are different levels of severity of MDS, it’s not a type of leukaemia but can sometimes lead to acute myeloid leukaemia. MDS is rare – about 4 in every 100,000 people get MDS.  It mainly affects older people, and is more common in people over 70 years old.
If you have low or intermediate risk MDS you may not need treatment straightaway, but regular blood transfusions and medication can help. Some people with more severe MDS can have chemotherapy and a small number of people may need to have a stem cell transplant
MDS Patient Support UK offer more information and support.
Blood cancer symptoms

Some common blood cancer symptoms include:

Fever, chills
Persistent fatigue, weakness
Loss of appetite, nausea
Unexplained weight loss
Night sweats
Bone/joint pain
Abdominal discomfort
Headaches
Shortness of breath
Frequent infections
Itchy skin or skin rash
Swollen lymph nodes in the neck, underarms, groin

Leukemia marked by an acute destruction of health sustaining red blood cells includes the symptoms of anemia, weakness and extreme fatigue. Consequently one affected by it is likely to sweat and come under bouts of breath shortness in course of performing day to day activities of the regular kind. Vulnerability to infection and swelling of the lymph nodes are some of the other fallouts of Leukemia. Blood tests are likely to present higher counts of white blood corpuscles.

Blood cancer treatment & therapy options

Treatment for blood cancer depends on the type of cancer, your age, how fast the cancer is progressing, where the cancer has spread and other factors. Some common blood cancer treatments include:

Stem cell transplantation: A stem cell transplant infuses healthy blood-forming stem cells into the body. Stem cells can be collected from the bone marrow, circulating (peripheral) blood and umbilical cord blood.
Chemotherapy: Chemotherapy is the use of anticancer drugs designed to interfere with and halt the growth of cancer cells in the body. Chemotherapy for blood cancer sometimes consists of giving several drugs together in a set regimen. It may also be given before a stem cell transplant.
Radiation therapy: Radiation therapy may be used to destroy cancer cells or to relieve pain or discomfort. It may also be given before a stem cell transplant.
Symptoms pertaining to lymphoma.

One of the most common symptoms of lymphoma includes swollen lymphatic node because this cancer essentially revolves around the lymphatic cells. The swelling is mostly painless in nature. Some of the other indications include loss of weight and appetite, fever, sudden bouts of chill and night sweating.

Certain variety of leukemia is also associated with coughing, fatigue, fullness of abdomen and extreme fatigue. Itching, nausea and food aversion may also set in.

Symptoms pertaining to myeloma.

The initial stage may well go free of symptoms. But with the gradual prognosis of the disease, there ought to be generic feel of fatigue, painful back, susceptibility to infection, breath shortness, bouts of numbness and that of chest pain. Kidney problems are likely to develop on account of myeloma. Blood tests taken are likely to indicate abnormal clusters of plasma cells.
Depends on the rate of metastasis.

There are different yards sticks to distinguish blood cancer into different stages according to the symptoms of prognosis and rate of metastasis.

Four different phases of chronic leukemia.

The first phase is marked by an enlarged presence of lymph nodes. This happens owing to the spurt in the count of lymphocytes. The risk level at this stage is intermediate because at this stage of prognosis, the cancer is yet to spread and affect other physical organs.

The second stage is marked by the enlarged presence of spleen as well as liver; in addition to that of the lymph nodes. If not both the organs, at least one of them apart from lymph nodes is affected at the second stage. There is a massive swing in the growth of lymphocytes. The risk level is still moderate.
The next stage or the third stage is marked by the development of anemia. The aforementioned organs are still likely to remain swollen. In general two or more organs are likely to be affected at the third stage of cancerous development.

The fourth and last phase is marked by a drastic fall in the rate of blood platelets. In the last stage the cancerous development can also affect lungs besides the ones already affected. Anemia is likely to be more acute. Both the third as well as the last phase are more risky from the viewpoint of the sufferer.
Curability of blood cancer and the stages involved

The latest piece of news with regard to the curability of blood cancer.

According, to one of the most recent findings, researchers have come up with a curative alternative to blood cancer. The medication seeks to block the release of irregular enzymes accountable for the metastasis of blood cancer. Surfeit of protein accountable for the enlargement and increase of cancerous cells are likely to be blocked as well by the researched medication.

Even until some years back, it couldn't be categorically affirmed as to the curable deals of blood cancer. But according to the practitioners and faculty involved in research oriented studies, the first stage of blood cancer responded better to the deals of curability more than the others.

To go by the practitioners and advocates of alternate therapeutic measures to cancer cure, blood cancer is curable even in its second and the third stages.

Natural treatment of blood cancer

Some of the common avenues of treatment.

Other than chemo and radiotherapy, the conventional modes of treatment for blood cancer include attempts at stem cells and bone marrow transplantations.

Herbal deals in leukemia/blood cancer cure.

Certain herbs, at least two varieties of herbs known by the names of 'Garcinia Mangostana' and 'xanothenes' have been found to be effective with respect of leukemia. The herbs and compounds based on them have reflected intrinsic potential of growth inhibiting features.

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Blood Cancer: Myeloma - causes, symptoms and treatment
Importance of antioxidants.

It has commonly been observed that people particularly the kids undergoing treatment for blood cancer, respond better to curative measures if there isn't a drastic cut in the intensity of antioxidants. So, even with allopathic remedial options, it is important to go for a diet rich in greens and antioxidants, in order to add to the supportive base of the treatment.

Children oriented to a balanced diet with an adequate supply of greens and raw fruits are less likely to develop blood cancer/leukemia.
Treatments for blood cancer

When it comes to deciding on the best treatment, it all depends what type of blood cancer you have, how advanced and aggressive it is and your general health. Your doctor will suggest the most effective course of treatment for you.
Common treatments are chemotherapy, radiotherapy and, in some cases, a stem cell or bone marrow transplant.
What is chemotherapy?
Chemotherapy involves taking drugs that destroy cancer cells, hopefully putting it into remission or significantly slowing down the progression of the disease.
There are many types of chemotherapy drugs and they work in different ways. Sometimes doctors will prescribe a single drug, but often they’ll recommend combining two or more because they often work better together. Chemotherapy can be used on its own, but it’s often combined with other treatments like radiotherapy. Chemotherapy is designed to attack cells that are growing and multiplying. That’s because cancer cells grow and multiply faster than healthy cells.
Some healthy cells can be caught in the crossfire, as they can also be growing and dividing quickly. This can cause side effects such as nausea, tiredness and hair loss.
If you’re getting ready for a stem cell, bone marrow or cord blood transplant, you’ll also need chemotherapy to suppress your immune system and stop it attacking your donor’s new ‘foreign’ cells. This is called conditioning therapy.
What is radiotherapy?
Radiotherapy works by using high-energy X-rays to kill cancer cells.
For it to be effective, doctors need to give just the right amount of radiation, targeted at the right area of the body. That’s why you get radiotherapy in specialist centres where doctors, physicists and radiographers work together. They’ll normally use a machine called a ‘linear accelerator’ for the treatment.
Radiotherapy can treat some types of leukaemia and lymphoma. Doctors can also use it to prepare a patient for a stem cell, bone marrow or cord blood transplant as part of the conditioning therapy. A low dose of radiation will lower someone’s immune system, so they’re less likely to reject donor cells. The type of radiotherapy you might have before a stem cell transplant is called total body irradiation or TBI and this means it affects the whole body.
Radiotherapy can also damage normal cells, which can cause side effects. These vary greatly for each person; some experiencing mild symptoms such as tiredness while for others it can be more debilitating.  These side effects will normally have passed within a few weeks of the treatment finishing.
When radiotherapy finishes, most of your body's healthy cells will continue to grow normally again. But radiotherapy can have long-term side effects.
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Cancer is a group of diseases that can cause almost any sign or symptom. The signs and symptoms will depend on where the cancer is, how big it is, and how much it affects the organs or tissues. If a cancer has spread (metastasized), signs or symptoms may appear in different parts of the body.

As a cancer grows, it can begin to push on nearby organs, blood vessels, and nerves. This pressure causes some of the signs and symptoms of cancer. If the cancer is in a critical area, such as certain parts of the brain, even the smallest tumor can cause symptoms.

But sometimes cancer starts in places where it won’t cause any signs or symptoms until it has grown quite large. Cancers of the pancreas, for example, usually don’t cause symptoms until they grow large enough to press on nearby nerves or organs (this causes back or belly pain). Others may grow around the bile duct and block the flow of bile. This causes the eyes and skin to look yellow (jaundice). By the time a pancreatic cancer causes signs or symptoms like these, it’s usually in an advanced stage. This means it has grown and spread beyond the place it started – the pancreas.

A cancer may also cause symptoms like fever, extreme tiredness (fatigue), or weight loss. This may be because cancer cells use up much of the body’s energy supply, or they may release substances that change the way the body makes energy from food. Cancer can also cause the immune system to react in ways that produce these signs and symptoms.

Sometimes, cancer cells release substances into the bloodstream that cause symptoms that are not usually linked to cancer. For example, some cancers of the pancreas can release substances that cause blood clots in veins of the legs. Some lung cancers make hormone-like substances that raise blood calcium levels. This affects nerves and muscles, making the person feel weak and dizzy.

How are signs and symptoms helpful?
Treatment works best when cancer is found early – while it’s still small and is less likely to have spread to other parts of the body. This often means a better chance for a cure, especially if the cancer can be removed with surgery.

A good example of the importance of finding cancer early is melanoma skin cancer. It can be easy to remove if it has not grown deep into the skin. The 5-year survival rate (percentage of people who live at least 5 years after diagnosis) at this early stage is around 98%. Once melanoma has spread to other parts of the body, the 5-year survival rate drops to about 16%.

Sometimes people ignore symptoms. Maybe they don’t know that the symptoms could mean something is wrong. Or they might be frightened by what the symptoms could mean and don’t want to get medical help. Maybe they just can’t afford to get medical care.

Some symptoms, such as tiredness or coughing, are more likely caused by something other than cancer. Symptoms can seem unimportant, especially if there’s a clear cause or the problem only lasts a short time. In the same way, a person may reason that a symptom like a breast lump is probably a cyst that will go away by itself. But no symptom should be ignored or overlooked, especially if it has lasted a long time or is getting worse.

Most likely, symptoms are not caused by cancer, but it’s important to have them checked out, just in case. If cancer is not the cause, a doctor can help figure out what the cause is and treat it, if needed.

Sometimes, it’s possible to find cancer before having symptoms. The American Cancer Society and other health groups recommend cancer-related check-ups and certain tests for people even though they have no symptoms. This helps find certain cancers early, before symptoms start. For more information on early detection tests, see our document called American Cancer Society Guidelines for the Early Detection of Cancer. But keep in mind, even if you have these recommended tests, it’s still important to see a doctor if you have any symptoms.

What are some general signs and symptoms of cancer?
You should know some of the general signs and symptoms of cancer. But remember, having any of these does not mean that you have cancer – many other things cause these signs and symptoms, too. If you have any of these symptoms and they last for a long time or get worse, please see a doctor to find out what’s going on.

Unexplained weight loss

Most people with cancer will lose weight at some point. When you lose weight for no known reason, it’s called an unexplained weight loss. An unexplained weight loss of 10 pounds or more may be the first sign of cancer. This happens most often with cancers of the pancreas, stomach, esophagus (swallowing tube), or lung.

Fever

Fever is very common with cancer, but it more often happens after cancer has spread from where it started. Almost all people with cancer will have fever at some time, especially if the cancer or its treatment affects the immune system. (This can make it harder for the body to fight infection.) Less often, fever may be an early sign of cancer, such as blood cancers like leukemia or lymphoma.

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